1994年

111. Bigby, T. D., Lee, D. M., Minami, M., Ohishi, N., Shimizu, T., and Baker, J. R. (1994) Characterization of human airway epithelial cell leukotriene A4 hydrolase. Am. J. Respir. Cell Mol. Biol. 11, 615-624.

110. Shirasaki, H., Nishikawa, M., Adcock, I. M., Mak, J. C., Sakamoto, T., Shimizu, T., and Barnes, P. J. (1994) Expression of platelet-activating factor receptor mRNA in human and guinea pig lung. Am. J. Respir. Cell Mol. Biol. 10, 533-537.

109. Mutoh, H., Ishii, S., Izumi, T., Kato, S., and Shimizu, T. (1994) Platelet-activating factor (PAF) positively auto-regulates the expression of human PAF receptor transcript 1 (leukocyte-type) through NF-κB. Biochem. Biophys. Res. Commun. 205, 1137-1142.

108. Mutoh, H., Kume, K., Sato, S., Kato, S., and Shimizu, T. (1994) Positive and negative regulations of human platelet-activating factor receptor transcript 2 (tissue-type) by estrogen and TGF-β1. Biochem. Biophys. Res. Commun. 205, 1130-1136.

107. Sakanaka, C., Ferby, I., Waga, I., Bito, H., and Shimizu, T. (1994) On the mechanism of cytosolic phospholipase A2 activation in CHO cells carrying somatostatin receptor: wortmannin-sensitive pathway to activate mitogen-activated protein kinase. Biochem. Biophys. Res. Commun. 205, 18-23.

106. Kobayashi, Y., Shimazaki, T., Kawajiri, K., Shimizu, T., Seyama, Y., and Sato, F. (1994) Important contribution of the methylene part of LTB4 toward binding affinity to the LTB4 receptors and rise in intracellular-free calcium concentration. Biochim. Biophys. Acta. 1215, 280-284.

105. Bito, H., Honda, Z., Nakamura, M., and Shimizu, T. (1994) Cloning, expression and tissue distribution of rat platelet-activating-factor-receptor cDNA. Eur. J. Biochem. 221, 211-218.

104. Liu, B., Nakashima, S., Kanoh, H., Takano, T., Shimizu, T., and Nozawa, Y. (1994) Activation of phospholipase D in Chinese hamster ovary cells expressing platelet-activating factor receptor. J. Biochem. 116, 882-891.

103. Ferby, I.M., Waga, I., Sakanaka, C., Kume, K., and Shimizu, T. (1994) Wortmannin inhibits mitogen-activated protein kinase activation induced by platelet-activating factor in guinea pig neutrophils. J. Biol. Chem. 269, 30485-30488.

102. Takano, T., Honda, Z., Sakanaka, C., Izumi, T., Kameyama, K., Haga, K., Haga, T., Kurokawa, K., and Shimizu, T. (1994) Role of cytoplasmic tail phosphorylation sites of platelet-activating factor receptor in agonist-induced desensitization. J. Biol. Chem. 269, 22453-22458.

101. Bito, H., Mori, M., Sakanaka, C., Takano, T., Honda, Z., Gotoh, Y., Nishida, E., and Shimizu, T. (1994) Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade. J. Biol. Chem. 269, 12722-12730.

100. Honda, Z., Takano, T., Gotoh, Y., Nishida, E., Ito, K., and Shimizu, T. (1994) Transfected platelet-activating factor receptor activates mitogen-activated protein (MAP) kinase and MAP kinase kinase in Chinese hamster ovary cells. J. Biol. Chem. 269, 2307-2315.

99. Kajihara, A., Komooka, H., Kamiya, K., Yoneda, T., Yoneda, S., Nakamura, M., Shimizu, T., and Umeyama, H. (1994) Three-dimensional model of the human PAF receptor. J. Lipid Mediat. Cell Signal 9, 185-196.

98. Tsuge, H., Ago, H., Aoki, M., Furuno, M., Noma, M., Miyano, M., Minami, M., Izumi, T., and Shimizu, T. (1994) Crystallization and preliminary X-ray crystallographic studies of recombinant human leukotriene A4 hydrolase complexed with bestatin. J. Mol. Biol. 238, 854-856.