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111. Bigby, T. D., Lee, D. M., Minami, M., Ohishi, N., Shimizu, T., and Baker, J. R. (1994) Characterization of human airway epithelial cell leukotriene A4 hydrolase. Am. J. Respir. Cell Mol. Biol. 11, 615-624.

110. Shirasaki, H., Nishikawa, M., Adcock, I. M., Mak, J. C., Sakamoto, T., Shimizu, T., and Barnes, P. J. (1994) Expression of platelet-activating factor receptor mRNA in human and guinea pig lung. Am. J. Respir. Cell Mol. Biol. 10, 533-537.

109. Mutoh, H., Ishii, S., Izumi, T., Kato, S., and Shimizu, T. (1994) Platelet-activating factor (PAF) positively auto-regulates the expression of human PAF receptor transcript 1 (leukocyte-type) through NF-κB. Biochem. Biophys. Res. Commun. 205, 1137-1142.

108. Mutoh, H., Kume, K., Sato, S., Kato, S., and Shimizu, T. (1994) Positive and negative regulations of human platelet-activating factor receptor transcript 2 (tissue-type) by estrogen and TGF-β1. Biochem. Biophys. Res. Commun. 205, 1130-1136.

107. Sakanaka, C., Ferby, I., Waga, I., Bito, H., and Shimizu, T. (1994) On the mechanism of cytosolic phospholipase A2 activation in CHO cells carrying somatostatin receptor: wortmannin-sensitive pathway to activate mitogen-activated protein kinase. Biochem. Biophys. Res. Commun. 205, 18-23.

106. Kobayashi, Y., Shimazaki, T., Kawajiri, K., Shimizu, T., Seyama, Y., and Sato, F. (1994) Important contribution of the methylene part of LTB4 toward binding affinity to the LTB4 receptors and rise in intracellular-free calcium concentration. Biochim. Biophys. Acta. 1215, 280-284.

105. Bito, H., Honda, Z., Nakamura, M., and Shimizu, T. (1994) Cloning, expression and tissue distribution of rat platelet-activating-factor-receptor cDNA. Eur. J. Biochem. 221, 211-218.

104. Liu, B., Nakashima, S., Kanoh, H., Takano, T., Shimizu, T., and Nozawa, Y. (1994) Activation of phospholipase D in Chinese hamster ovary cells expressing platelet-activating factor receptor. J. Biochem. 116, 882-891.

103. Ferby, I.M., Waga, I., Sakanaka, C., Kume, K., and Shimizu, T. (1994) Wortmannin inhibits mitogen-activated protein kinase activation induced by platelet-activating factor in guinea pig neutrophils. J. Biol. Chem. 269, 30485-30488.

102. Takano, T., Honda, Z., Sakanaka, C., Izumi, T., Kameyama, K., Haga, K., Haga, T., Kurokawa, K., and Shimizu, T. (1994) Role of cytoplasmic tail phosphorylation sites of platelet-activating factor receptor in agonist-induced desensitization. J. Biol. Chem. 269, 22453-22458.

101. Bito, H., Mori, M., Sakanaka, C., Takano, T., Honda, Z., Gotoh, Y., Nishida, E., and Shimizu, T. (1994) Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade. J. Biol. Chem. 269, 12722-12730.

100. Honda, Z., Takano, T., Gotoh, Y., Nishida, E., Ito, K., and Shimizu, T. (1994) Transfected platelet-activating factor receptor activates mitogen-activated protein (MAP) kinase and MAP kinase kinase in Chinese hamster ovary cells. J. Biol. Chem. 269, 2307-2315.

99. Kajihara, A., Komooka, H., Kamiya, K., Yoneda, T., Yoneda, S., Nakamura, M., Shimizu, T., and Umeyama, H. (1994) Three-dimensional model of the human PAF receptor. J. Lipid Mediat. Cell Signal 9, 185-196.

98. Tsuge, H., Ago, H., Aoki, M., Furuno, M., Noma, M., Miyano, M., Minami, M., Izumi, T., and Shimizu, T. (1994) Crystallization and preliminary X-ray crystallographic studies of recombinant human leukotriene A4 hydrolase complexed with bestatin. J. Mol. Biol. 238, 854-856.