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Review

47.Valentine, WJ., Shimizu, T., Shindou, H. Lysophospholipid acyltransferases orchestrate the compositional diversity of phospholipids. Biochimie. 2023 in press

46.Nakamaura, M. and Shimizu, T. (2023) Therapeutic target of leukotriene B4 receptors, BLT1 and BLT2: insights from basic research. Biochimie, 214, 2023

45.Yanagida, K., Shimizu, T. (2023) Lysophosphatidic acid, a simple phospholipid with myriad functions. Lysophosphatidic acid, a simple phospholipid with myriad functions. Pharmacology & Therapeutics 246, June 2023, 108421. 

44.Yokomizo, T., Shimizu, T. (2023) The leukotriene B4 receptors BLT1 and BLT2 as potential therapeutic targets. Immunol Rev. 2023;00:1-12. doi:10.1111/imr.13196

43. Nakamura, M., and Shimizu, T. (2022) Recent advances in function and structure of two leukotriene B4 receptors: BLT1 and BLT2. Biochem Pharmacol. Jul 15; 115178.

42.Harayama, T., and Shimizu, T. (2020). Roles of polyunsaturated fatty acids, from mediators to membrane. J. Lipid Res.  61, 1150-1160.

41. Kita, Y.*, Shindou, H.*, and Shimizu, T. (2018) Cytosolic phospholipase A2 and lysophospholipid acyltransferases. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 838-845
*, equal contribution

40. Yokomizo, T., Nakamura, M., Shimizu, T. (2018) Leukotriene receptors as potential therapeutic targets.  J. Clin. Invest. 128, 2691-2701.

39. Hishikawa, D., Valentine, J.W., Iizuka-Hishikawa, Y., Shindou, H., Shimizu, T. (2017) Metabolism and functions of docosahexaenoic acid-containing membrane glycerophospholipids. FEBS Lett. 591. 2730-2744.

38.Kita, Y., Tokuoka-M., S., and Shimizu, T. (2017) Mediator lipidomics by liquid chromatography-tandem mass spectrometry. BBA-Molecular and Cell Biology of Lipids. 1862. 777-781

37. Antonny, B., Vanni, S., Shindou, H., and Ferreira, T. (2015) From zero to six double bonds: phospholipid unsaturation and organelle functions. Trends in Cell Biology. 25:427-36. doi: 10.1016/j.tcb.

36. Hishikawa, D., Hashidate, T., Shimizu, T., and  Shindou, H. (2014) Diversity and function of membrane glycerophospholipids generated by the remodeling pathway in mammalian cells. J. Lipid   Res. 55:799-807

35. Shindou H, Hishikawa D, Harayama T, Eto M and Shimizu T (2013) Generation of membrane   diversity by lysophospholipid acyltransferases J. Biochem. 154. 21-8.

34. Yanagida, K., Kurikawa, Y., Shimizu, T., and Ishii, S. (2013) Current progress in non-Edg family LPA receptor research. Biochim Biophys Acta. ;1831:33-41.

33. Nakamura, M., and Shimizu, T. (2011) Leukotriene Receptors. Chem. Rev. 111, 6231-6298.

32. Nakamura, M., Yasuda, D., Hirota, N., and Shimizu, T. (2010) Specific ligands as pharmacological chaperons: The transport of misfolded G-protein coupled receptors to the cell surface. IUBMB Life 62, 453-459.

31. Shindou, H., Hishikawa, D., Harayama, T., Yuki, K., and Shimizu, T. (2009) Recent progress on Acyl-CoA: lysophospholipid acyltransferase research. J. Lipid Res. 50, S46-S51.

30. Shimizu, T. (2009) Lipid mediators in health and disease: Enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation. Ann. Rev. Pharmacol. Toxicol. 49, 123-150.

29. Shindou, H. and Shimizu, T. (2009) Acyl-CoA:lysophospholipid acyltransferases. J. Biol. Chem. 284, 1-5.

28. Hikiji, H., Takato, T., Shimizu, T., and Ishii, S. (2008) The roles of prostanoids, leukotrienes, and platelet-activating factor in bone metabolism and disease. Prog. Lipid Res. 47, 107-126.

27. Taguchi, R., Nishijima, M., and Shimizu, T. (2007) Basic analytical systems for lipidomics by mass spectrometry in Japan. Methods Enzymol. 432, 185-211.

26. Shimizu, T., Ohto, T., and Kita, Y. (2006) Cytosolic phospholipase A2: Biochemical properties and physiological roles. IUBMB Life 58, 328-333.

25. Fahy, E., Subramaniam, S., Brown, A., Glass, C. K., Merrill, A. H., Jr., Murphy, R. C., Raetz, E. R. H., Russell, D. W., Seyama, Y., Shaw, W., Shimizu, T., Spener, F., van Meer, G., VanNieuwenhze, M. S., Stephen H. White, S. H., Witztum, J. L., and Dennis, E. A. (2005) A comprehensive classification system for lipids J. Lipid Res. 46, 839-862.

24. Shimizu, T., Yokomizo, T., and Izumi, T. (2003) Characterizationof two distinct types of leukotriene B4 receptors. Oxygen and Life: Oxygenases, Oxidase, and Lipid Mediators (Ishimura, Y., Nozaki, M. Yamamoto, S., Shimizu, T., Narumiya, S., and Mitani, F. eds) pp 415-420, Elsevier, Amsterdam.

23. Wong, D. A., Uozumi, N., Kita, Y., and Shimizu, T. (2003) Cytosolic phospholipase A2α in mouse platelets. Adv. Exp. Med. Biol. 525, 81-86.

22. Brink, C., Dahle'n, S.K., Drazen, J., Evans, J.F., Hay, D.W.P., Nicosia, S., Serhan, C.N., Shimizu, T., and Yokomizo, T. (2003) International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors. Pharmacol. Rev. 55, 195-227.

21. Ishii, S., Nagase, T., and Shimizu, T. (2002) Platelet-activating factor receptor. Prostaglandins Other Lipid Mediat. 68-69, 599-609.

20. Toda, A, Yokomizo, T, and Shimizu, T. (2002) Leukotriene B4 receptors. Prostaglandins Other Lipid Mediat. 68-69, 575-585.

19. Uozumi, N., and Shimizu,T. (2002) Roles for cytosolic phospholipase A2α as revealed by gene-targeted mice. Prostaglandins Other Lipid Mediat. 68-69, 59-69.

18. Izumi, T., Yokomizo, T., Obinata, H., Ogasawara, H., and Shimizu, T. (2002) Leukotriene receptors: classification, gene expression, and signal transduction. J. Biochem. 132, 1-6.

17. Honda, Z., Ishii, S., and Shimizu, T. (2002) Platelet-activating factor receptor. J. Biochem. 131, 773-779.

16. Shimizu, T. (2002) Leukotriene receptors. in Wiley Encyclopedia of Molecular Medicine 5, 1920-1921.

15. Yokomizo, T., Izumi, T., and Shimizu, T. (2001) Leukotriene B4: metabolism and signal transduction. Arch. Biochem. Biophys. 385, 231-241.

14. Shimizu, T. (2001) Biological control by lipid mediators and pathophysiology. Jap. Med. Assoc. J. 44, 369-374.

13. Hirabayashi, T., and Shimizu, T. (2000) Localization and regulation of cytosolic phospholipase A2. Biochim. Biophys. Acta. 1488, 124-138.

12. Yokomizo, T., Masuda, K., Kato, K., Toda, A., Izumi, T., and Shimizu, T. (2000) Leukotriene B4 receptor. Cloning and intracellular signaling. Am. J. Resp. Crit. Care Med. 161, S51-55.

11. Ishii, S., and Shimizu, T. (2000) Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice. Prog. Lipid Res. 39, 41-82.

10. Shimizu, T., and Mutoh, H. (1997) Structure and regulation of platelet activating factor receptor gene. Adv. Exp. Med. Biol. 407, 197-204.

9. Shimizu, T., Mutoh, H., and Kato, S. (1996) Platelet-activating factor receptor. Gene structure and tissue-specific regulation. Adv. Exp. Med. Biol. 416, 79-84.

8. Shimizu, T., Mori, M., Bito, H., Sakanaka, C., Tabuchi, S., Aihara, M., and Kume, K. (1996) Platelet-activating factor and somatostatin activate mitogen-activated protein kinase (MAP kinase) and arachidonate release. J. Lipid Mediat. Cell Signal 14, 103-108.

7. Yokomizo, T., Uozumi, N., Takahashi, T., Kume, K., Izumi, T., and Shimizu, T. (1995) Leukotriene A4 hydrolase and leukotriene B4 metabolism. J. Lipid Mediat. Cell Signal 12, 321-332.

6. Izumi, T., and Shimizu, T. (1995) Platelet-activating factor receptor: gene expression and signal transduction. Biochim. Biophys. Acta. 1259, 317-333.

5. Mori, M., Bito, H., Sakanaka, C., Honda, Z., Kume, K., Izumi, T., and Shimizu, T. (1994) Activation of mitogen-activated protein kinase and arachidonate release via two G-protein-coupled receptor expressed in the rat hippocampus. Ann. N.Y. Acad. Sci. 744, 107-125.

4. Shimizu, T., Mutoh, H., Waga, I., Nakamura, M., Honda, Z., and Izumi, T. (1994) Structure and function of platelet-activating factor receptor. in Molecular Basis of Inflammation, (Navarro, J. ed) pp 163-167, Ares Serono Symposia Publication, Rome.

3. Honda, Z., and Shimizu, T. (1993) Lipid mediators in defence mechanisms. in The Natural Immune System: Humoral Factors, (Sim, E. ed.) pp. 337-367. IRL Press at Oxford University Press, Oxford.

2. Shimizu, T, Honda, Z., Nakamura, M., Bito, H., and Izumi, T. (1992) Platelet-activating factor receptor and signal transduction. Biochem. Pharmacol. 44, 1001-1008.

1. Shimizu, T., and Wolfe, L. S. (1990) Arachidonic acid cascade and signal transduction. J. Neurochem. 55, 1-15.